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International Atherosclerosis
Society
Literature e-Newsletter
August 2007

Stethoscope, medicine, world, fruit, lab
 
RESEARCH TOPICS:
purple bullet Drug Therapy
red bullet Epidemiology
orange bullet Genetics of Cardiovascular Disease
orange bullet Imaging
orange bullet Lipidomics
purple bullet Oxidative Stress / Antioxidants
red bullet Risk Factors
blue bullet Stroke

IAS WEBSITE EDITORIAL BOARD
red bullet Editor-in-Chief
Scott M. Grundy, MD, PhD
Dallas, TX, USA
orange bullet Associate Editors
Stefano Bellosta
Milan, Italy
Emanuela Folco
Milan, Italy
Ann Jackson
Houston, TX, USA
green bullet Website Editors
Gianpaolo Bagnato
Milan, Italy
Annamaria Scimone
Milan, Italy
Mandi Wong
Dallas, TX, USA

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The International Atherosclerosis Society Literaure
e-Newsletter is a monthly compilation of the latest
research articles on atherosclerosis.

orange bullet Apo/Lipoprotein

Oxidation of chylomicron remnant-like particles inhibits their uptake by THP-1 macrophages by apolipoprotein E-dependent processes.
Authors: Bejta F, Moore EH, Avella M, Gough PJ, Suckling KE, Botham KM.
Journal: Biochim Biophys Acta. 2007 Jul;1771(7):901-10. Epub 2007 May 3
.
View Abstract

Utility of non-high-density lipoprotein cholesterol versus other lipoprotein measures in detecting subclinical atherosclerosis in young adults (The Bogalusa Heart Study).
Authors: Frontini MG, Srinivasan SR, Xu JH, Tang R, Bond MG, Berenson G.
Journal: Am J Cardiol. 2007 Jul 1;100(1):64-8. Epub 2007 May 11
.
View Abstract

(1)H NMR investigation on interaction between ibuprofen and lipoproteins.
Authors: Lan W, Zhu H, Zhou Z, Ye C, Liu M.
Journal: Chem Phys Lipids. 2007 Aug;148(2):105-111. Epub 2007 May 10.

View Abstract

Analysis of modified apolipoprotein B-100 structures formed in oxidized low-density lipoprotein using LC-MS/MS.
Authors: Obama T, Kato R, Masuda Y, Takahashi K, Aiuchi T, Itabe H.
Journal: Proteomics. 2007 Jul;7(13):2132-41.

View Abstract

Low dose apolipoprotein A-I rescues carotid arteries from inflammation in vivo.
Authors: Puranik R, Bao S, Nobecourt E, Nicholls SJ, Dusting GJ, Barter PJ, Celermajer DS, Rye KA.
Journal: Atherosclerosis. 2007 Jun 22; [Epub ahead of print]

View Abstract

Where are we with high-density lipoprotein raising and inhibition of cholesteryl ester transfer for heart disease risk reduction?
Authors: Schaefer EJ, Asztalos BF.
Journal: Curr Opin Cardiol. 2007 Jul;22(4):373-8.

View Abstract

(1)H NMR at 800MHz facilitates detailed phospholipid follow-up during atherogenic modifications in low density lipoproteins.
Authors: Soininen P, Oorni K, Maaheimo H, Laatikainen R, Kovanen PT, Kaski K, Ala-Korpela M.
Journal: Biochem Biophys Res Commun. 2007 Aug 17;360(1):290-4. Epub 2007 Jun 18.

View Abstract

POPC/apoA-I discs as a potent lipoprotein modulator in Tangier disease.
Authors: Uehara Y, Tsuboi Y, Zhang B, Miura SI, Baba Y, Higuchi MA, Yamada T, Rye KA, Saku K.
Journal: Atherosclerosis. 2007 Jun 7; [Epub ahead of print]

View Abstract

Lipoprotein-associated phospholipase A2 predicts 5-year cardiac mortality independently of established risk factors and adds prognostic information in patients with low and medium high-sensitivity C-reactive protein (the ludwigshafen risk and cardiovascular health study).
Authors: Winkler K, Hoffmann MM, Winkelmann BR, Friedrich I, Schafer G, Seelhorst U, Wellnitz B, Wieland H, Boehm BO, Marz W.
Journal: Clin Chem. 2007 Aug;53(8):1440-7. Epub 2007 Jun 15.

View Abstract

High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory.
Authors: Gharavi NM, Gargalovic PS, Chang I, Araujo JA, Clark MJ, Szeto WL, Watson AD, Lusis AJ, Berliner JA.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1346-53. Epub 2007 Mar 22.

View Abstract

Secretion of Apolipoprotein E From Macrophages Occurs via a Protein Kinase A and Calcium-Dependent Pathway Along the Microtubule Network.
Kockx M, Guo DL, Huby T, Lesnik P, Kay J, Sabaretnam T, Jary E, Hill M, Gaus K, Chapman J, Stow JL, Jessup W, Kritharides L.
Circ Res. 2007 Jul 27; [Epub ahead of print]

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green bullet Biomarkers

The relative impact of different measures of adiposity on markers of early atherosclerosis.
Authors: Stamatelopoulos KS, Lekakis JP, Vamvakou G, Katsichti P, Protogerou A, Revela I, Karatzi K, Alevizaki M, Zakopoulos N, Papamichael CM.
Journal: Int J Cardiol. 2007 Jul 10;119(2):139-46. Epub 2006 Oct 11.

View Abstract

Association of blood pressure and fitness with levels of atherosclerotic risk markers pre-exercise and post-exercise.
Authors: von Kanel R, Hong S, Pung MA, Mills PJ.
Journal: Am J Hypertens. 2007 Jun;20(6):670-5.

View Abstract

Differential association of hemoglobin with pro-inflammatory high density lipoproteins in atherogenic/hyperlipidemic mice - a novel biomarker of atherosclerosis.
Authors: Watanabe J, Chou KJ, Liao JC, Miao Y, Meng HH, Ge H, Grijalva V, Hama S, Kozak K, Buga G, Whitelegge JP, Lee TD, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST.
Journal: J Biol Chem. 2007 Jun 7; [Epub ahead of print]

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blue bullet Diabetes

Serum levels of sRAGE, the soluble form of receptor for advanced glycation end products, are associated with inflammatory markers in patients with type 2 diabetes.
Authors: Nakamura K, Yamagishi S, Adachi H, Kurita-Nakamura Y, Matsui T, Yoshida T, Imaizumi T.
Journal: Mol Med. 2007 Mar-Apr;13(3-4):185-9.

View Abstract

Effects of insulin dependence on inflammatory process, thrombotic mechanisms and endothelial function, in patients with type 2 diabetes mellitus and coronary atherosclerosis.
Authors: Antoniades C, Tousoulis D, Marinou K, Papageorgiou N, Bosinakou E, Tsioufis C, Stefanadi E, Latsios G, Tentolouris C, Siasos G, Stefanadis C.
Journal: Clin Cardiol. 2007 Jun;30(6):295-300.

View Abstract

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.
Authors: Furuhashi M, Tuncman G, Gorgun CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS.
Journal: Nature. 2007 Jun 21;447(7147):959-65. Epub 2007 Jun 6.

View Abstract

Dyslipidemia in type 2 diabetes mellitus.
Authors: Gadi R, Samaha FF.
Journal: Curr Diab Rep. 2007 Jun;7(3):228-34.

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purple bullet Drug Therapy

Understanding eNOS for pharmacological modulation of endothelial function: a translational view.
Authors: Braam B, Verhaar MC.
Journal: Curr Pharm Des. 2007;13(17):1727-40. Review.

View Abstract

Caveolae and caveolin-1: novel potential targets for the treatment of cardiovascular disease.
Authors: Frank PG, Hassan GS, Rodriguez-Feo JA, Lisanti MP.
Journal: Curr Pharm Des. 2007;13(17):1761-9. Review.

View Abstract

Growth factor therapy in atherosclerotic disease-friend or foe.
Authors: Hoefer IE, Timmers L, Piek JJ.
Journal: Curr Pharm Des. 2007;13(17):1803-10. Review.

View Abstract

Vascular benefits of angiotensin receptor blockers.
Author: Voors AA.
Journal: Expert Opin Investig Drugs. 2007 Jul;16(7):987-97. Review.

View Abstract

Rosuvastatin restores superoxide dismutase expression and inhibits accumulation of oxidized LDL in the aortic arch of obese dyslipidemic mice.
Verreth W, De Keyzer D, Davey PC, Geeraert B, Mertens A, Herregods MC, Smith G, Desjardins F, Balligand JL, Holvoet P. Br J Pharmacol. 2007 Jun;151(3):347-55. Epub 2007 Mar 26.
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purple bullet Epidemiology

Prevalence, recognition and treatment of cardiovascular risk factors in outpatients with atherothrombosis in Israel.
Authors: Barski L, Porath A, Novack V, Jotkowitz A.
Journal: Isr Med Assoc J. 2007 May;9(5):376-9.

View Abstract

Association between cardiorespiratory fitness and prevalence of carotid atherosclerosis among men with hypertension.
Authors: Jae SY, Carnethon MR, Heffernan KS, Choi YH, Lee MK, Fernhall B.
Journal: Am Heart J. 2007 Jun;153(6):1001-5.

View Abstract

Whole-grain intake and carotid artery atherosclerosis in a multiethnic cohort: the Insulin Resistance Atherosclerosis Study.
Authors: Mellen PB, Liese AD, Tooze JA, Vitolins MZ, Wagenknecht LE, Herrington DM.
Journal: Am J Clin Nutr. 2007 Jun;85(6):1495-502.

View Abstract

Overview of dietary influences on atherosclerotic vascular disease: epidemiology and prevention.
Authors: Thomas GN, Cheung BM, Ho SY, Macfarlane DJ, Deng HB, McGhee SM, Woo J, Lam TH, Tomlinson B.
Journal: Cardiovasc Hematol Disord Drug Targets. 2007 Jun;7(2):87-97. Review.

View Abstract

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red bullet Genetics of Cardiovascular Disease

What is the relationship among atherosclerosis markers, apolipoprotein E polymorphism and dementia?
Authors: Altamura C, Squitti R, Pasqualetti P, Tibuzzi F, Silvestrini M, Ventriglia MC, Cassetta E, Rossini PM, Vernieri F.
Journal: Eur J Neurol. 2007 Jun;14(6):679-82.

View Abstract

Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet.
Authors: Harrington SC, Simari RD, Conover CA.
Journal: Circ Res. 2007 Jun 22;100(12):1696-702. Epub 2007 May 17.

View Abstract

Hereditary and environmental influences on arterial function.
Authors: Hayward CS, Benetos A.
Journal: Clin Exp Pharmacol Physiol. 2007 Jul;34(7):658-64. Review.

View Abstract

Vascular stiffness and genetic variation at the endothelial nitric oxide synthase locus: the Framingham Heart study.
Authors: Mitchell GF, Guo CY, Kathiresan S, Vasan RS, Larson MG, Vita JA, Keyes MJ, Vyas M, Newton-Cheh C, Musone SL, Camargo AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ.
Journal: Hypertension. 2007 Jun;49(6):1285-90. Epub 2007 Apr 2.

View Abstract

Frequency of paraoxonase 192/55 polymorphism in an Iranian population.
Authors: Sepahvand F, Rahimi-Moghaddam P, Shafiei M, Ghaffari SM, Rostam-Shirazi M, Mahmoudian M.
Journal: J Toxicol Environ Health A. 2007 Jul;70(13):1125-9.

View Abstract

Effects of the renin-angiotensin system genes and salt sensitivity genes on blood pressure and atherosclerosis in the total population and patients with type 2 diabetes.
Authors: Yazdanpanah M, Aulchenko YS, Hofman A, Janssen JA, Sayed-Tabatabaei FA, van Schaik RH, Klungel OH, Stricker BH, Pols HA, Witteman JC, Lamberts SW, Oostra BA, van Duijn CM.
Journal: Diabetes. 2007 Jul;56(7):1905-12. Epub 2007 Apr 19.

View Abstract

The cholesteryl ester transfer protein I405V polymorphism is associated with increased high-density lipoprotein levels and decreased risk of myocardial infarction: the Rotterdam Study.
Authors: Isaacs A, Sayed-Tabatabaei FA, Hofman A, Oostra BA, Klungel OH, Maitland-Vander Zee AH, Stricker BH, Witteman JC, van Duijn CM.
Journal: Eur J Cardiovasc Prev Rehabil. 2007 Jun;14(3):419-21.

View Abstract

Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study.
Authors: Volcik K, Ballantyne CM, Pownall HJ, Sharrett AR, Boerwinkle E.
Journal: J Stud Alcohol Drugs. 2007 Jul;68(4):485-92.

View Abstract

Effect of the -420C/G variant of the resistin gene promoter on metabolic syndrome, obesity, myocardial infarction and kidney dysfunction.
Authors: Norata GD, Ongari M, Garlaschelli K, Tibolla G, Grigore L, Raselli S, Vettoretti S, Baragetti I, Noto D, Cefalu AB, Buccianti G, Averna M, Catapano AL.
Journal: J Intern Med. 2007 Jul;262(1):104-12.

View Abstract

Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause, and cardiovascular mortality.
Marz W, Seelhorst U, Wellnitz B, Tiran B, Obermayer-Pietsch B, Renner W, Boehm BO, Ritz E, Hoffmann MM.
J Clin Endocrinol Metab. 2007 Jun;92(6):2363-9. Epub 2007 Mar 20.
View Abstract

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orange bullet Imaging

Carotid plaque inflammation detected by 18F-fluorodeoxyglucose-positron emission tomography. Pilot study.
Authors: Arauz A, Hoyos L, Zenteno M, Mendoza R, Alexanderson E.
Journal: Clin Neurol Neurosurg. 2007 Jun;109(5):409-12. Epub 2007 Apr 5.

View Abstract

Imaging techniques for the vulnerable coronary plaque.
Authors: Cademartiri F, La Grutta L, Palumbo A, Maffei E, Aldrovandi A, Malago R, Alberghina F, Pugliese F, Runza G, Belgrano M, Midiri M, Cova MA, Krestin GP.
Journal: Radiol Med (Torino). 2007 Jul 24; [Epub ahead of print]

View Abstract

Increased echolucency of carotid plaques in patients with type 2 diabetes.
Authors: Ostling G, Hedblad B, Berglund G, Goncalves I.
Journal: Stroke. 2007 Jul;38(7):2074-8. Epub 2007 May 24.

View Abstract

Association of high-density lipoprotein levels and carotid atherosclerotic plaque characteristics by magnetic resonance imaging.
Authors: Phan BA, Chu B, Polissar N, Hatsukami TS, Yuan C, Zhao XQ.
Journal: Int J Cardiovasc Imaging. 2007 Jun;23(3):337-42. Epub 2006 Nov 4.

View Abstract

Identification of atherosclerotic lipid deposits by diffusion-weighted imaging.
Authors: Qiao Y, Ronen I, Viereck J, Ruberg FL, Hamilton JA.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1440-6. Epub 2007
Mar 22.

View Abstract

MDCT angiography of the renal arteries in patients with atherosclerotic renal artery stenosis: implications for renal artery stenting with distal protection.
Authors: Talenfeld AD, Schwope RB, Alper HJ, Cohen EI, Lookstein RA.
Journal: AJR Am J Roentgenol. 2007 Jun;188(6):1652-8.

View Abstract

The topography of aortic atherosclerosis enhances its precision as a predictor of stroke.
Authors: van der Linden J, Bergman P, Hadjinikolaou L.
Journal: Ann Thorac Surg. 2007 Jun;83(6):2087-92.

View Abstract

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green bullet Immunology

Enhanced immune system activation and arterial inflammation accelerates atherosclerosis in lupus-prone mice.
Authors: Gautier EL, Huby T, Ouzilleau B, Doucet C, Saint-Charles F, Gremy G, Chapman MJ, Lesnik P.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1625-31. Epub 2007 Apr 19.

View Abstract

Mast cells: multipotent local effector cells in atherothrombosis.
Authors: Kovanen PT.
Journal: Immunol Rev. 2007 Jun;217:105-22. Review.

View Abstract

Basic science for the clinician 44: atherosclerosis: an immunologically mediated (autoimmune?) disease.
Author: Sigal LH.
Journal: J Clin Rheumatol. 2007 Jun;13(3):160-8. Review.

View Abstract

Accumulation of immune cells and high expression of chemokines/chemokine receptors in the upstream shoulder of atherosclerotic carotid plaques.
Authors: Yilmaz A, Lipfert B, Cicha I, Schubert K, Klein M, Raithel D, Daniel WG, Garlichs CD.
Journal: Exp Mol Pathol. 2007 Jun;82(3):245-55. Epub 2007 Jan 12

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blue bullet Inflammation

Postprandial inflammation and endothelial dysfuction.
Authors: Alipour A, Elte JW, van Zaanen HC, Rietveld AP, Cabezas MC.
Journal: Biochem Soc Trans. 2007 Jun;35(Pt 3):466-9.

View Abstract

Carotid plaque inflammation detected by 18F-fluorodeoxyglucose-positron emission tomography. Pilot study.
Authors: Arauz A, Hoyos L, Zenteno M, Mendoza R, Alexanderson E.
Journal: Clin Neurol Neurosurg. 2007 Jun;109(5):409-12. Epub 2007 Apr 5.

View Abstract

Delta-like 4 induces notch signaling in macrophages: implications for inflammation.
Authors: Fung E, Tang SM, Canner JP, Morishige K, Arboleda-Velasquez JF, Cardoso AA, Carlesso N, Aster JC, Aikawa M.
Journal: Circulation. 2007 Jun 12;115(23):2948-56. Epub 2007 May 28.

View Abstract

Enhanced immune system activation and arterial inflammation accelerates atherosclerosis in lupus-prone mice.
Authors: Gautier EL, Huby T, Ouzilleau B, Doucet C, Saint-Charles F, Gremy G, Chapman MJ, Lesnik P.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1625-31. Epub 2007 Apr 19.

View Abstract

Endotoxin-induced effects on platelets and monocytes in an in vivo model of inflammation.
Authors: Kalsch T, Elmas E, Nguyen XD, Suvajac N, Kluter H, Borggrefe M, Dempfle CE.
Journal: Basic Res Cardiol. 2007 Jul 13; [Epub ahead of print]

View Abstract

Platelets, inflammation and atherosclerosis.
Authors: Lindemann S, Kramer B, Seizer P, Gawaz M.
Journal: J Thromb Haemost. 2007 Jul;5 Suppl 1:203-11.

View Abstract

Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man.
Authors: Luchtefeld M, Schunkert H, Stoll M, Selle T, Lorier R, Grote K, Sagebiel C, Jagavelu K, Tietge UJ, Assmus U, Streetz K, Hengstenberg C, Fischer M, Mayer B, Maresso K, El Mokhtari NE, Schreiber S, Muller W, Bavendiek U, Grothusen C, Drexler H, Trautwein C, Broeckel U, Schieffer B.
Journal: J Exp Med. 2007 Jul 30; [Epub ahead of print]

View Abstract

Left ventricular hypertrophy, subclinical atherosclerosis, and inflammation.
Authors: Mehta SK, Rame JE, Khera A, Murphy SA, Canham RM, Peshock RM, de Lemos JA, Drazner MH.
Journal: Hypertension. 2007 Jun;49(6):1385-91. Epub 2007 Apr 2.

View Abstract

Both cyclooxygenase- and cytokine-mediated inflammation are associated with carotid intima-media thickness.
Authors: Wohlin M, Helmersson J, Sundstrom J, Arnlov J, Vessby B, Larsson A, Andren B, Lind L, Basu S.
Journal: Cytokine. 2007 Jul 16; [Epub ahead of print]

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blue bullet Lipid and Lipoprotein Metabolism

Regulation of protein C inhibitor (PCI) activity by specific oxidized and negatively charged phospholipids.
Authors: Malleier JM, Oskolkova O, Bochkov V, Jerabek I, Sokolikova B, Perkmann T, Breuss J, Binder BR, Geiger M.
Journal: Blood. 2007 Jun 1;109(11):4769-76. Epub 2007 Mar 1.

View Abstract

Intestinal cholesterol transport proteins: an update and beyond.
Authors: Levy E, Spahis S, Sinnett D, Peretti N, Maupas-Schwalm F, Delvin E, Lambert M, Lavoie MA.
Journal: Curr Opin Lipidol. 2007 Jun;18(3):310-8. Review.

View Abstract

Bile acids, farnesoid X receptor, atherosclerosis and metabolic control. Kuipers F, Stroeve JH, Caron S, Staels B.
Curr Opin Lipidol. 2007 Jun;18(3):289-97. Review.

View Abstract

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purple bullet Lipidomics

Developmental changes in rat surfactant lipidomics in the context of species variability.
Authors: Bernhard W, Schmiedl A, Koster G, Orgeig S, Acevedo C, Poets CF, Postle AD.
Journal: Pediatr Pulmonol. 2007 Jul 20;42(9):794-804 [Epub ahead of print]

View Abstract

Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.
Authors: Kolak M, Westerbacka J, Velagapudi VR, Wagsater D, Yetukuri L, Makkonen J, Rissanen A, Hakkinen AM, Lindell M, Bergholm R, Hamsten A, Eriksson P, Fisher RM, Oresic M, Yki-Jarvinen H.
Journal: Diabetes. 2007 Aug;56(8):1960-8. Epub 2007 Jul 9.

View Abstract

Top-down lipidomic screens by multivariate analysis of high-resolution survey mass spectra.
Authors: Schwudke D, Hannich JT, Surendranath V, Grimard V, Moehring T, Burton L, Kurzchalia T, Shevchenko A.
Journal: Anal Chem. 2007 Jun 1;79(11):4083-93. Epub 2007 May 3.

View Abstract

Exploring the lipoprotein composition using Bayesian regression on serum lipidomic profiles.
Authors: Sysi-Aho M, Vehtari A, Velagapudi VR, Westerbacka J, Yetukuri L, Bergholm R, Taskinen MR, Yki-Jarvinen H, Oresic M.
Journal: Bioinformatics. 2007 Jul 1;23(13):i519-i528.

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red bullet Menopause

Differential effects of 17beta-estradiol on function and expression of estrogen receptor alpha, estrogen receptor beta, and GPR30 in arteries and veins of patients with atherosclerosis.
Authors: Haas E, Meyer MR, Schurr U, Bhattacharya I, Minotti R, Nguyen HH, Heigl A, Lachat M, Genoni M, Barton M.
Journal: Hypertension. 2007 Jun;49(6):1358-63. Epub 2007 Apr 23.

View Abstract

Carotid atherosclerosis associated to metabolic syndrome but not BMI in healthy menopausal women.
Authors: Montalcini T, Gorgone G, Gazzaruso C, Sesti G, Perticone F, Pujia A.
Journal: Diabetes Res Clin Pract. 2007 Jun;76(3):378-82. Epub 2006 Oct 10.

View Abstract

Postmenopausal oral estrogen therapy affects hemostatic factors, but does not account for reduction in the progression of subclinical atherosclerosis.
Authors: Vigen C, Hodis HN, Chandler WL, Lobo RA, Mack WJ.
Journal: J Thromb Haemost. 2007 Jun;5(6):1201-8.

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orange bullet Metabolic Syndrome

Metabolic syndrome is not associated with markers of subclinical atherosclerosis, serum adiponectin and endogenous androgen concentrations in Japanese men with Type 2 diabetes.
Authors: Fukui M, Ose H, Kitagawa Y, Kamiuchi K, Nakayama I, Ohta M, Obayashi H, Yamasaki M, Hasegawa G, Yoshikawa T, Nakamura N.
Journal: Diabet Med. 2007 Jun 25; [Epub ahead of print]

View Abstract

The effects of metabolic syndrome versus infectious burden on inflammation, severity of coronary atherosclerosis, and major adverse cardiovascular events.
Authors: Dai DF, Lin JW, Kao JH, Hsu CN, Chiang FT, Lin JL, Chou YH, Hsu KL, Tseng CD, Tseng YZ, Hwang JJ.
Journal: J Clin Endocrinol Metab. 2007 Jul;92(7):2532-7. Epub 2007 Apr 10.

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green bullet Nutrition and Diet

Associations between markers of subclinical atherosclerosis and dietary patterns derived by principal components analysis and reduced rank regression in the Multi-Ethnic Study of Atherosclerosis (MESA).
Authors: Nettleton JA, Steffen LM, Schulze MB, Jenny NS, Barr RG, Bertoni AG, Jacobs DR Jr.
Journal: Am J Clin Nutr. 2007 Jun;85(6):1615-25.

View Abstract

Dietary fat-induced alterations in atherosclerosis are abolished by ACAT2-deficiency in ApoB100 only, LDLr-/- mice.
Authors: Bell TA 3rd, Kelley K, Wilson MD, Sawyer JK, Rudel LL. Journal: Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1396-402. Epub 2007 Apr 12.
View Abstract

Mulberry leaf powder prevents atherosclerosis in apolipoprotein E-deficient mice.
Authors: Harauma A, Murayama T, Ikeyama K, Sano H, Arai H, Takano R, Kita T, Hara S, Kamei K, Yokode M.
Journal: Biochem Biophys Res Commun. 2007 Jul 6;358(3):751-6. Epub 2007 May 7.

View Abstract

Whole-grain intake and carotid artery atherosclerosis in a multiethnic cohort: the Insulin Resistance Atherosclerosis Study.
Authors: Mellen PB, Liese AD, Tooze JA, Vitolins MZ, Wagenknecht LE, Herrington DM.
Journal: Am J Clin Nutr. 2007 Jun;85(6):1495-502.
View Abstract

L-arginine plus atorvastatin for prevention of atheroma formation in genetically hypercholesterolaemic rabbits.
Authors: Rasmusen C, Moinard C, Martin C, Tricottet V, Cynober L, Couderc R.
Journal: Br J Nutr. 2007 Jun;97(6):1083-9. Epub 2007 Mar 29.

View Abstract

Overview of dietary influences on atherosclerotic vascular disease: epidemiology and prevention.
Authors: Thomas GN, Cheung BM, Ho SY, Macfarlane DJ, Deng HB, McGhee SM, Woo J, Lam TH, Tomlinson B.
Journal: Cardiovasc Hematol Disord Drug Targets. 2007 Jun;7(2):87-97. Review.

View Abstract

Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice.
Authors: Saraswathi V, Gao L, Morrow JD, Chait A, Niswender KD, Hasty AH.
Journal: J Nutr. 2007 Jul;137(7):1776-82.

View Abstract

Reduction of atherosclerotic nanoplaque formation and size by Ginkgo biloba (EGb 761) in cardiovascular high-risk patients.
Rodriguez M, Ringstad L, Schafer P, Just S, Hofer HW, Malmsten M, Siegel G.
Atherosclerosis. 2007 Jun;192(2):438-44. Epub 2007 Mar 29.

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purple bullet Oxidative Stress / Antioxidants

Oxidative stress-mediated arterial dysfunction in patients with metabolic syndrome: Effect of ascorbic acid.
Authors: Cangemi R, Angelico F, Loffredo L, Del Ben M, Pignatelli P, Martini A, Violi F.
Journal: Free Radic Biol Med. 2007 Sep 1;43(5):853-9. Epub 2007 Jun 13.

View Abstract

Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior.
Authors: Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH.
Journal: J Am Coll Cardiol. 2007 Jun 26;49(25):2379-93. Epub 2007 Jun 8. Review.

View Abstract

Reactive carbonyls and oxidative stress: Potential for therapeutic intervention.
Author: Ellis EM.
Journal: Pharmacol Ther. 2007 Jul;115(1):13-24. Epub 2007 May 8.

View Abstract

Effect of Pentoxifylline on inflammatory burden, oxidative stress and platelet aggregability in hypertensive type 2 diabetes mellitus patients.
Authors: Maiti R, Agrawal NK, Dash D, Pandey BL.
Journal: Vascul Pharmacol. 2007 Aug-Sep;47(2-3):118-24. Epub 2007 Jun 2.

View Abstract

Gone with the Wnts: {beta}-catenin, TCF, FOXO, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism.
Authors: Manolagas SC, Almeida M.
Journal: Mol Endocrinol. 2007 Jul 10; [Epub ahead of print]

View Abstract

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors.
Authors: Negre-Salvayre A, Coatrieux C, Ingueneau C, Salvayre R.
Journal: Br J Pharmacol. 2007 Jul 23; [Epub ahead of print]

View Abstract

Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis.
Authors: Orozco LD, Kapturczak MH, Barajas B, Wang X, Weinstein MM, Wong J, Deshane J, Bolisetty S, Shaposhnik Z, Shih DM, Agarwal A, Lusis AJ, Araujo JA.
Journal: Circ Res. 2007 Jun 22;100(12):1703-11. Epub 2007 May 10.

View Abstract

Mechanisms for oxidative stress in diabetic cardiovascular disease.
Authors: Pennathur S, Heinecke JW.
Journal: Antioxid Redox Signal. 2007 Jul;9(7):955-69.

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Native C-reactive protein induces endothelial dysfunction in ApoE(-/-) mice: Implications for iNOS and reactive oxygen species.
Authors: Schwedler SB, Kuhlencordt PJ, Ponnuswamy PP, Hatiboglu G, Quaschning T, Widder J, Wanner C, Potempa LA, Galle J.
Journal: Atherosclerosis. 2007 Jul 30; [Epub ahead of print]

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Farnesyltransferase inhibitor, manumycin a, prevents atherosclerosis development and reduces oxidative stress in apolipoprotein E-deficient mice.
Authors: Sugita M, Sugita H, Kaneki M.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1390-5. Epub 2007 Mar 15.

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Tanshinone II A attenuates atherosclerotic calcification in rat model by inhibition of oxidative stress.
Authors: Tang F, Wu X, Wang T, Wang P, Li R, Zhang H, Gao J, Chen S, Bao L, Huang H, Liu P.
Journal: Vascul Pharmacol. 2007 Jun;46(6):427-38. Epub 2007 Jan 23.

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Atherosclerosis and Oxidant Stress: The End of the Road for Antioxidant Vitamin Treatment?
Thomson MJ, Puntmann V, Kaski JC.
Cardiovasc Drugs Ther. 2007 Jun;21(3):195-210.

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Both cyclooxygenase- and cytokine-mediated inflammation are associated with carotid intima-media thickness.
Wohlin M, Helmersson J, Sundstrom J, Arnlov J, Vessby B, Larsson A, Andren B, Lind L, Basu S.
Cytokine. 2007 Jul 16; [Epub ahead of print]

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Anti-oxidant and anti-atherogenic properties of liposomal glutathione: Studies in vitro, and in the atherosclerotic apolipoprotein E-deficient mice.
Authors: Rosenblat M, Volkova N, Coleman R, Aviram M.
Journal: Atherosclerosis. 2007 Jun 21; [Epub ahead of print]

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Increased expression of glutathione reductase in macrophages decreases atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice.
Authors: Qiao M, Kisgati M, Cholewa JM, Zhu W, Smart EJ, Sulistio MS, Asmis R.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1375-82. Epub 2007 Mar 15.

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Farnesyltransferase inhibitor, manumycin a, prevents atherosclerosis development and reduces oxidative stress in apolipoprotein E-deficient mice.
Authors: Sugita M, Sugita H, Kaneki M.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1390-5. Epub 2007
Mar 15.

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gray bullet Pediatrics

Traditional and "new" cardiovascular risk markers and factors in pediatric dialysis patients.
Authors: Civilibal M, Caliskan S, Oflaz H, Sever L, Candan C, Canpolat N, Kasapcopur O, Bugra Z, Arisoy N.
Journal: Pediatr Nephrol. 2007 Jul;22(7):1021-9. Epub 2007 Mar 6.

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Age of onset of type 1 diabetes in children and carotid intima medial thickness.
Authors: Dalla Pozza R, Bechtold S, Bonfig W, Putzker S, Kozlik-Feldmann R, Netz H, Schwarz HP.
Journal: J Clin Endocrinol Metab. 2007 Jun;92(6):2053-7. Epub 2007 Mar 20.

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Antioxidant enzyme activities, lipid peroxidation, and total antioxidant status in children with Henoch-Schonlein purpura.
Authors: Ece A, Kelekci S, Kocamaz H, Hekimoglu A, Balik H, Yolbas I, Erel O.
Journal: Clin Rheumatol. 2007 Jul 24; [Epub ahead of print]

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Statin Treatment in Children With Familial Hypercholesterolemia. The Younger, the Better.
Authors: Rodenburg J, Vissers MN, Wiegman A, van Trotsenburg AS, van der Graaf A, de Groot E, Wijburg FA, Kastelein JJ, Hutten BA.
Journal: Circulation. 2007 Jul 30; [Epub ahead of print]

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Early atherosclerosis in childhood type 1 diabetes: role of raised systolic blood pressure in the absence of dyslipidaemia.
Authors: Schwab KO, Doerfer J, Krebs A, Krebs K, Schorb E, Hallermann K, Superti-Furga A, Zieger B, Marz W, Schmidt-Trucksass A, Winkler K.
Journal: Eur J Pediatr. 2007 Jun;166(6):541-8. Epub 2007 Mar 27.

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red bullet Plaque Biology

Proteomics analysis of human coronary atherosclerotic plaque: a feasibility study of direct tissue proteomics by liquid chromatography and tandem mass spectrometry.
Authors: Bagnato C, Thumar J, Mayya V, Hwang SI, Zebroski H, Claffey KP, Haudenschild C, Eng JK, Lundgren DH, Han DK.
Journal: Mol Cell Proteomics. 2007 Jun;6(6):1088-102. Epub 2007 Mar 5.

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Biomarkers of atherosclerosis and the potential of MRI for the diagnosis of vulnerable plaque.
Authors: Canet-Soulas E, Letourneur D.
Journal: MAGMA. 2007 Jun;20(3):129-42. Epub 2007 Jun 29.

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Chlamydia pneumoniae and symptomatic carotid atherosclerotic plaque: a prospective study.
Authors: Gagliardi RJ, Silveira DR, Caffaro RA, dos Santos VP, Caiaffa-Filho HH.
Journal: Arq Neuropsiquiatr. 2007 Jun;65(2B):385-9.

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Increased spatial vasa vasorum density in the proximal LAD in hypercholesterolemia--implications for vulnerable plaque-development.
Authors: Gossl M, Versari D, Mannheim D, Ritman EL, Lerman LO, Lerman A.
Journal: Atherosclerosis. 2007 Jun;192(2):246-52. Epub 2006 Aug 21.

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Plaque progression and regression in atherothrombosis.
Authors: Ibanez B, Vilahur G, Badimon JJ.
Journal: J Thromb Haemost. 2007 Jul;5 Suppl 1:292-9.

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The expression of vascular dendritic cells in human atherosclerotic carotid plaques.
Authors: Kawahara I, Kitagawa N, Tsutsumi K, Nagata I, Hayashi T, Koji T.
Journal: Hum Pathol. 2007 Jun 5; [Epub ahead of print]

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Inhibition of Progression and Stabilization of Plaques by Postnatal Interferon-{gamma} Function Blocking in ApoE-Knockout Mice.
Authors: Koga M, Kai H, Yasukawa H, Yamamoto T, Kawai Y, Kato S, Kusaba K, Kai M, Egashira K, Kataoka Y, Imaizumi T.
Journal: Circ Res. 2007 Jul 5; [Epub ahead of print]

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Pathological mechanisms of erythrocyte-induced vulnerability of atherosclerotic plaques.
Authors: Lin HL, Xu XS, Lu HX, Li CJ, Tang MX, Sun HW, Zhang Y.
Journal: Med Hypotheses. 2007 Jun 28; [Epub ahead of print]

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Influence of Residual Stress/Strain on the Biomechanical Stability of Vulnerable Coronary Plaques: Potential Impact for Evaluating the Risk of Plaque Rupture.
Authors: Ohayon J, Dubreuil O, Tracqui P, Le Floc'h S, Rioufol G, Chalabreysse L, Thivolet F, Pettigrew R, Finet G.
Journal: Am J Physiol Heart Circ Physiol. 2007 Jun 29; [Epub ahead of print]

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Association of high-density lipoprotein levels and carotid atherosclerotic plaque characteristics by magnetic resonance imaging.
Authors: Phan BA, Chu B, Polissar N, Hatsukami TS, Yuan C, Zhao XQ.
Journal: Int J Cardiovasc Imaging. 2007 Jun;23(3):337-42. Epub 2006 Nov 4.

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Localization to atherosclerotic plaque and biodistribution of biochemically derivatized superparamagnetic iron oxide nanoparticles (SPIONs) contrast particles for magnetic resonance imaging (MRI).
Authors: Smith BR, Heverhagen J, Knopp M, Schmalbrock P, Shapiro J, Shiomi M, Moldovan NI, Ferrari M, Lee SC.
Journal: Biomed Microdevices. 2007 Jun 12; [Epub ahead of print]

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green bullet Renal Disease

Searching for biomarker patterns characterizing carotid atherosclerotic burden in patients with reduced renal function.
Authors: Addabbo F, Mallamaci F, Leonardis D, Tripepi R, Tripepi G, Goligorsky MS, Zoccali C.
Journal: Nephrol Dial Transplant. 2007 Jul 21; [Epub ahead of print]

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Cardiovascular disease and subsequent kidney disease.
Authors: Elsayed EF, Tighiouart H, Griffith J, Kurth T, Levey AS, Salem D, Sarnak MJ, Weiner DE.
Journal: Arch Intern Med. 2007 Jun 11;167(11):1130-6.

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Atherogenic scavenger receptor modulation in the tubulointerstitium in response to chronic renal injury.
Authors: Okamura DM, Lopez-Guisa JM, Koelsch K, Collins S, Eddy AA.
Journal: Am J Physiol Renal Physiol. 2007 Aug;293(2):F575-85. Epub 2007 May 30.

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Chronic kidney disease: effects on the cardiovascular system.
Authors: Schiffrin EL, Lipman ML, Mann JF.
Journal: Circulation. 2007 Jul 3;116(1):85-97. Review.

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green bullet Risk Factors

Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study.
Authors: Cao JJ, Arnold AM, Manolio TA, Polak JF, Psaty BM, Hirsch CH, Kuller LH, Cushman M
Journal: Circulation. 2007 Jul 3;116(1):32-8. Epub 2007 Jun 18.

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Tobacco smoke exposure is associated with attenuated endothelial function in 11-year-old healthy children.
Kallio K, Jokinen E, Raitakari OT, Hamalainen M, Siltala M, Volanen I, Kaitosaari T, Viikari J, Ronnemaa T, Simell O.
Circulation. 2007 Jun 26;115(25):3205-12. Epub 2007 Jun 4.

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Resialylation of sialic acid deficit vascular endothelium, circulating cells and macromolecules may counteract the development of atherosclerosis: a hypothesis.
Lindberg G.
Atherosclerosis. 2007 Jun;192(2):243-5. Epub 2007 Apr 8.

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Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis.
Orozco LD, Kapturczak MH, Barajas B, Wang X, Weinstein MM, Wong J, Deshane J, Bolisetty S, Shaposhnik Z, Shih DM, Agarwal A, Lusis AJ, Araujo JA.
Circ Res. 2007 Jun 22;100(12):1703-11. Epub 2007 May 10.

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Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism.
Prasad K, Lee P.
Atherosclerosis. 2007 Jun;192(2):313-22. Epub 2006 Sep 11.

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Is the anti-inflammatory effect of regular exercise responsible for reduced cardiovascular disease?
Wilund KR.
Clin Sci (Lond). 2007 Jun;112(11):543-55. Review.

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blue bullet Stroke

Differential effect of soluble intercellular adhesion molecule-1 on the progression of atherosclerosis as compared to arterial thrombosis: A prospective analysis of the Women's Health Study.
Albert MA, Glynn RJ, Buring JE, Ridker PM.
Atherosclerosis. 2007 Jul 17; [Epub ahead of print]

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Carotid Plaque, Stroke Pathogenesis, and CRP: Treatment of Ischemic Stroke.
Krupinski J, Turu MM, Slevin M, Martinez-Gonzalez J.
Curr Treat Options Cardiovasc Med. 2007 Jun;9(3):229-235.

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gray bullet Vascular Biology

Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet.
Authors: Mehta JL, Sanada N, Hu CP, Chen J, Dandapat A, Sugawara F, Satoh H, Inoue K, Kawase Y, Jishage K, Suzuki H, Takeya M, Schnackenberg L, Beger R, Hermonat PL, Thomas M, Sawamura T.
Journal: Circ Res. 2007 Jun 8;100(11):1634-42. Epub 2007 May 3.
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Adenovirus-mediated expression of human paraoxonase 3 protects against the progression of atherosclerosis in apolipoprotein E-deficient mice.
Authors: Ng CJ, Bourquard N, Hama SY, Shih D, Grijalva VR, Navab M, Fogelman AM, Reddy ST.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1368-74. Epub 2007 Apr 19.

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Grb2 is required for atherosclerotic lesion formation.
Authors: Proctor BM, Ren J, Chen Z, Schneider JG, Coleman T, Lupu TS, Semenkovich CF, Muslin AJ.
Journal: Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1361-7. Epub 2007
Mar 15.

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blue bullet Vascular Calcification / Calcium Signaling

The good and the bad in the link between insulin resistance and vascular calcification.
Fadini GP, Pauletto P, Avogaro A, Rattazzi M.
Atherosclerosis. 2007 Aug;193(2):241-4. Epub 2007 Jul 2.

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Relation of aortic valve calcium to myocardial ischemic perfusion in individuals with a low coronary artery calcium score.
Ho J, FitzGerald S, Cannaday J, Stolfus L, Weilbacher D, Henderson Y, Newman T, Whitehead R, Radford N.
Am J Cardiol. 2007 Jun 1;99(11):1535-7. Epub 2007 Apr

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High-normal fasting blood glucose in non-diabetic range is associated with increased coronary artery calcium burden in asymptomatic men.
Nasir K, Santos RD, Tufail K, Rivera J, Carvalho JA, Meneghello R, Brady TD, Blumenthal RS.
Atherosclerosis. 2007 Jun 30; [Epub ahead of print]

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Metabolic syndrome is associated with coronary artery calcium in asymptomatic white Brazilian men considered low-risk by Framingham risk score.
Santos RD, Nasir K, Tufail K, Meneghelo RS, Carvalho JA, Blumenthal RS. Prev Cardiol. 2007 Summer;10(3):141-6.
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